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Abstract #4290

Improved differentiation of Primaray liver cancer by combination of Amide Transfer weighted imaging(APTw) and T2 mapping

Tao Lin1, Jiazheng Wang2, Zhigang Wu2, Lihua Chen 1, Qingwei Song1, Renwang Pu1, Ying Zhao1, Xue Ren1, Qihao Xu1, and Ailian Liu1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China


Hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) are the most common types of primary liver cancer, which differ greatly in terms of pathogenesis, biological behavior, histological morphology, treatment and prognosis. The accurate diagnosis of HCC and ICC is important for treatment options. In this retrospective study, we revealed that APTw combined with T2 mapping could improve the differential diagnosis of HCC and ICC. Results showed that APTw combined with T2 mapping had higher efficacy (AUC:0.910). Further analysis also implied moderate correlations between APTw and T2 mapping.

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