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Abstract #4341

Differentiation between glioblastoma and solitary brain metastasis using mean apparent propagator-MRI: a Radiomics analysis

Xiaoyue Ma1, Guohua Zhao1, Eryuan Gao1, Jinbo Qi1, Kai Zhao1, Ankang Gao1, Jie Bai1, Huiting Zhang2, Xu Yan2, Guang Yang3, and Jingliang Cheng1
1The Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2MR Scientific Marketing, Siemens Healthineers, Shanghai, China, 3Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China


Preoperative differentiation of glioblastomas and solitary brain metastases may contribute to more appropriate treatment plans and follow-up. However, routine MRI has a very limited ability to distinguish between the two. Mean apparent propagator (MAP)-MRI, as a representative of diffusion MRI technology, is effective in evaluating the complexity and inhomogeneity of the brain microstructure. We developed a series of radiomics models of MAP-MRI parametric maps, routine MRI, combined routine MRI, and combined MAP-MRI parametric maps to compare their performance in the identification of two tumors. Finally, a good performance with the combined MAP-MRI radiomics model was obtained.

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