Abstract #4341

Differentiation between glioblastoma and solitary brain metastasis using mean apparent propagator-MRI: a Radiomics analysis

Xiaoyue Ma¹, Guohua Zhao¹, Eryuan Gao¹, Jinbo Qi¹, Kai Zhao¹, Ankang Gao¹, Jie Bai¹, Huiting Zhang², Xu Yan², Guang Yang³, and Jingliang Cheng¹

¹The Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²MR Scientific Marketing, Siemens Healthineers, Shanghai, China, ³Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China

Synopsis

Preoperative differentiation of glioblastomas and solitary brain metastases may contribute to more appropriate treatment plans and follow-up. However, routine MRI has a very limited ability to distinguish between the two. Mean apparent propagator (MAP)-MRI, as a representative of diffusion MRI technology, is effective in evaluating the complexity and inhomogeneity of the brain microstructure. We developed a series of radiomics models of MAP-MRI parametric maps, routine MRI, combined routine MRI, and combined MAP-MRI parametric maps to compare their performance in the identification of two tumors. Finally, a good performance with the combined MAP-MRI radiomics model was obtained.

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