Saturated Multi-delay Arterial Spin Labeling (SAMURAI) Technique for Simultaneous Perfusion and T1 Quantification of Kidneys
Zihan Ning1, Shuo Chen1, Zhensen Chen2, Hualu Han1, Huiyu Qiao1, Rui Shen1, Peng Wu3, and Xihai Zhao1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine Tsinghua University, Beijing, China, 2Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 3Philips Healthcare, Shanghai, China
We proposed a Saturated Multi-delay Arterial Spin Labeling (SAMURAI) technique with a correspondingly modified kinetic model to achieve simultaneous acquisitions of RBF, aBAT, tBAT and T1 map in kidney with a single scan. SAMURAI provided T1 map with excellent correlation (R2=0.976) compared with IR-SE. Compared with multi-TI FAIR, SAMURAI provided equally reliable ASL and T1 quantification results (ICC: 0.875-0.958) with excellent scan-rescan repeatability (ICC: 0.905-0.992) and significantly reduced scan time (45’ vs 4’6’’ for 9 TIs).
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