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Abstract #4386

Ultrafast B1 Mapping with RF-Prepared 3D FLASH Acquisition: Correcting the Bias due to T1-Induced k-Space Filtering Effect

Dan Zhu1,2 and Qin Qin1,2
1F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, 2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States


The traditional RF-prepared B1 mapping technique consists of one scan with an RF preparation module for FA-encoding and a second scan without this module for normalizing. To reduce the T1-induced k-space filtering effect, this method is limited to 2D FLASH acquisition with a two-parameter method. Based on the point spread function analysis of FLASH readout, a novel 3D RF-prepared three-parameter method for B1-mapping is proposed to correct the T1-induced quantification bias. The proposed technique was compared with existing methods in the brain, breast, and abdomen and demonstrated with high accuracy for ultrafast B1 mapping.

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