Abstract #4390

Three-dimensional echo-shifted echo planar imaging with simultaneous blip-up and blip-down acquisitions for correcting geometric distortion

Kaibao Sun¹, Zhifeng Chen^2,3, Guangyu Dan^1,4, Qingfei Luo¹, Alessandro Scotti¹, Lirong Yan^5,6, and Xiaohong Joe Zhou^1,4,7

¹Center for MR Research, University of Illinois at Chicago, Chicago, IL, United States, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Department of Radiology, Harvard Medical School, Charlestown, MA, United States, ⁴Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States, ⁵USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, ⁶Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, ⁷Departments of Radiology and Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States

Synopsis

Geometric distortion is a prevalent image artifact in echo planar imaging (EPI). In a method known as BUDA (blip-up/down acquisition), k-space model-based reconstruction of two EPI datasets acquired separately with opposing phase-encoding polarities has been shown to reduce image distortions. A main disadvantage is that the two-shot acquisition strategy doubles the scan time and increases vulnerability to motion. We herein introduce a novel sequence – 3D echo-shifted EPI with BUDA (esEPI-BUDA) – to address the aforementioned issues by integrating the two acquisitions into one shot. We have successfully applied the 3D esEPI-BUDA technique to functional MRI.

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