Three-dimensional echo-shifted echo planar imaging with simultaneous blip-up and blip-down acquisitions for correcting geometric distortion
Kaibao Sun1, Zhifeng Chen2,3, Guangyu Dan1,4, Qingfei Luo1, Alessandro Scotti1, Lirong Yan5,6, and Xiaohong Joe Zhou1,4,7
1Center for MR Research, University of Illinois at Chicago, Chicago, IL, United States, 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Department of Radiology, Harvard Medical School, Charlestown, MA, United States, 4Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States, 5USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, 6Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, 7Departments of Radiology and Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States
Geometric distortion is a prevalent image artifact in echo planar imaging (EPI). In a method known as BUDA (blip-up/down acquisition), k-space model-based reconstruction of two EPI datasets acquired separately with opposing phase-encoding polarities has been shown to reduce image distortions. A main disadvantage is that the two-shot acquisition strategy doubles the scan time and increases vulnerability to motion. We herein introduce a novel sequence – 3D echo-shifted EPI with BUDA (esEPI-BUDA) – to address the aforementioned issues by integrating the two acquisitions into one shot. We have successfully applied the 3D esEPI-BUDA technique to functional MRI.
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