Multidimensional relaxation correlation spectroscopic imaging methods have demonstrated powerful capabilities to resolve subvoxel microstructure. In this work, we perform T1-T2 relaxation correlation spectroscopic imaging using a sequence that combines MR fingerprinting with a ViSTa preparation module to enhance sensitivity to short-T1 components. We demonstrate theoretically and empirically that this approach has advantages over MR fingerprinting without ViSTa. Empirical results demonstrate the ability to identify at least 6 anatomically plausible tissue components, including a short-T1 component that was not previously resolved when using MR fingerprinting without ViSTa. A novel generalized ADMM algorithm is also proposed that substantially improves computational efficiency.
This abstract and the presentation materials are available to members only; a login is required.