Abstract #4443

Influence of Spatial Resolution in T2* Maps of Intramyocardial Hemorrhage

Xinheng Zhang^1,2, Hsin-Jung Yang¹, and Rohan Dharmakumar³

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Bioengineering Department, UCLA, Los Angeles, CA, United States, ³Krannert Cardiovascular Research Center, Indiana University School of Medicine, Indianapolis, IN, United States

Synopsis

The influence of spatial resolution on T2*-based characterization of hemorrhage within myocardial infarctions (MI) has not been investigated. We hypothesized that partial volume could play a critical role in the detection and quantification of hemorrhagic remnants. Ex-vivo pig hearts with 8-week old MI were imaged with multi-gradient echo sequences with various in-plane and through-plane spatial resolutions. Our findings show that optimal detection of hemorrhagic remnants with T2* MRI at 3T requires imaging voxels to be between 5 and 7 mm³.

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