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Abstract #4443

Influence of Spatial Resolution in T2* Maps of Intramyocardial Hemorrhage

Xinheng Zhang1,2, Hsin-Jung Yang1, and Rohan Dharmakumar3
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Bioengineering Department, UCLA, Los Angeles, CA, United States, 3Krannert Cardiovascular Research Center, Indiana University School of Medicine, Indianapolis, IN, United States


The influence of spatial resolution on T2*-based characterization of hemorrhage within myocardial infarctions (MI) has not been investigated. We hypothesized that partial volume could play a critical role in the detection and quantification of hemorrhagic remnants. Ex-vivo pig hearts with 8-week old MI were imaged with multi-gradient echo sequences with various in-plane and through-plane spatial resolutions. Our findings show that optimal detection of hemorrhagic remnants with T2* MRI at 3T requires imaging voxels to be between 5 and 7 mm3.

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