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Abstract #4463

Association and Prediction of Intracranial Plaque Characteristics and Hs-CRP Levels In Patients with Acute Cerebral Infarction

Rui-Ying Li1, Deng-Ling Zhao1, and Xian-Ce Zhao2
1Jiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China, 2Philips Healthcare, Shanghai, China

Synopsis

Atherosclerosis accompanied by inflammation is considered to be a crucial mechanism for patients with ischemic stroke. We aimed to investigate the association between intracranial plaque characteristics and high-sensitivity C-reactive protein (hs-CRP) levels to predict the occurrence of acute cerebral infarction (ACI). 85 patients with cerebral infarction were divided into ACI group and non-acute cerebral infarction (NACI) group. Hs-CRP levels were further grouped into low, intermediate and high groups. We concluded that elevated hs-CRP levels was independently associated with strong plaque enhancement, their synergistic effects provided incremental value in predicting the occurrence of acute cerebral infarction.

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