Abstract #4463

Association and Prediction of Intracranial Plaque Characteristics and Hs-CRP Levels In Patients with Acute Cerebral Infarction

Rui-Ying Li¹, Deng-Ling Zhao¹, and Xian-Ce Zhao²

¹Jiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China, ²Philips Healthcare, Shanghai, China

Synopsis

Atherosclerosis accompanied by inflammation is considered to be a crucial mechanism for patients with ischemic stroke. We aimed to investigate the association between intracranial plaque characteristics and high-sensitivity C-reactive protein (hs-CRP) levels to predict the occurrence of acute cerebral infarction (ACI). 85 patients with cerebral infarction were divided into ACI group and non-acute cerebral infarction (NACI) group. Hs-CRP levels were further grouped into low, intermediate and high groups. We concluded that elevated hs-CRP levels was independently associated with strong plaque enhancement, their synergistic effects provided incremental value in predicting the occurrence of acute cerebral infarction.

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