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Abstract #4462

Clinical features and CMR derived Left ventricular dysfunction in Obese Heart Failure with Preserved Ejection Fraction

jian he1, Jing Xu1, and Minjie Lu1
1fuwai hospital, Beijing, China


In this well-defined cohort of prospectively studied 101 obese Heart failure with preserved ejection fraction (HFpEF), 46 normal-weight HFpEF patients and 30 clinically healthy controls, we illustrated clinical features of obese HFpEF phenotype with more remarkable inflammation response, and cardiovascular magnetic resonance (CMR) derived left ventricular remodeling and worse subtle dysfunction, compared to normal-weight HFpEF and clinically healthy controls. In addition, diastolic dysfunction (impaired EGLSR, EGCSR, and EGRSR) and subtle systolic dysfunction were more prominent characteristics of obese HFpEF patients, showed modest to moderate correlations with body mass and estimated plasma volume, and assisted in the diagnosis of obese HFpEF.

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