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Abstract #4486

Adaptive-CS-Net to Accelerate 3D T1-weighted Imaging: Brain Volume Measures for clinical use

Sandeep Ganji1,2, Brian Johnson3,4, John Penatzer3, and Johannes M. Peeters5
1MR R&D, Philips Healthcare, Rochestr, MN, United States, 2Mayo Clinic, Rochester, MN, United States, 3Philips Healthcare, Gainesville, FL, United States, 4University of Texas Southwestern Medical Center, Dallas, TX, United States, 5Philips Healthcare, Eindhoven, Netherlands


Despite long scan times, 3D T1-weighted (T1w) MRI is routinely used for MRI studies to provide high resolution structural and volumetric information of brain. Volumetric analysis can serve as a biomarker and aid in clinical diagnosis of certain diseases such as Alzheimer’s, mild cognitive impairment, and atrophy, however, the standardized 3D T1-weighted scans suffer from long acquisition times well over 5 minutes. We compared the results of volumetric brain analysis for 3D T1w images acquired over a range of compressed SENSE acceleration factors with and without Adaptive-CS-Net reconstruction against a standard clinical 3D T1w MRI protocol.

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