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Abstract #4564

Non-linear Association Between NT-proBNP and Septal Native T1 in Non-ischaemic Dilated Cardiomyopathy

Yujie Gao1, Xiaoyue Zhou2, Shengen Liao3, and Yi Xu1
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2MR Collaboration, Siemens Healthcare, Shanghai, China, 3Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

Synopsis

This study investigated the relationship between cardiac magnetic resonance (CMR) T1 mapping parameters and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in non-ischaemic dilated cardiomyopathy (DCM) patients. The results showed that, in DCM, a non-linear relationship existed between NT-proBNP and septal native T1, indicating a complex relationship between the secretion of NT-proBNP and myocardial diffuse fibrosis. When NT-proBNP is greater than the inflection point(1105 pg/ml), NT-proBNP may provide additional value for the judgment of myocardial diffuse fibrosis.

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