Abstract #4564

Non-linear Association Between NT-proBNP and Septal Native T1 in Non-ischaemic Dilated Cardiomyopathy

Yujie Gao¹, Xiaoyue Zhou², Shengen Liao³, and Yi Xu¹

¹Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ²MR Collaboration, Siemens Healthcare, Shanghai, China, ³Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

Synopsis

This study investigated the relationship between cardiac magnetic resonance (CMR) T1 mapping parameters and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in non-ischaemic dilated cardiomyopathy (DCM) patients. The results showed that, in DCM, a non-linear relationship existed between NT-proBNP and septal native T1, indicating a complex relationship between the secretion of NT-proBNP and myocardial diffuse fibrosis. When NT-proBNP is greater than the inflection point(1105 pg/ml), NT-proBNP may provide additional value for the judgment of myocardial diffuse fibrosis.

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