The detection and localization of diffuse myocardial fibrosis is for the non-invasive evaluation of therapeutic strategies in murine cardiac disease models. Cardiac late-gadolinium enhancement (LGE) and T1 mapping are two techniques for non-invasive cardiovascular magnetic resonance (CMR) imaging. This abstract demonstrates that the magnetization prepared 2 rapid acquisition gradient echo (MP2RAGE) can simultaneously acquire LGE and T1 maps for the detection of diffuse myocardial fibrosis in a 1K/DOCA/salt-induced murine model of hypertensive disease.
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