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Abstract #4575

Multi-delay arterial spin labeling perfusion map may predict cerebral hyperperfusion after carotid endarterectomy

Xiaoyuan Fan1, Tianye Lin1, Juan Wei2, Jianxun Qu2, Zhentao Zuo1, and Feng Feng1
1Peking Union Medical College Hospital, Beijing, China, 2GE healthcare, Beijing, China


Preoperative measurement of cerebrovascular reactivity using acetazolamide or CO2 induced SPECT is the gold standard for predicting cerebral hyperperfusion (CH) after carotid endarterectomy (CEA). However, it is often impractical to perform SPECT examinations on all patients.

Arterial spin labeling (ASL) is a non-invasive technique to image the brain perfusion. Based on multi-delay ASL perfusion map, we extracted two hemodynamic parameters (cerebral blood flow and arterial transit time) and established a five-scale scoring system for the prediction of CH.

We found in patients with carotid stenosis, multi-delay ASL is a practical and reliable tool for the prediction of CH after CEA.

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