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Abstract #4576

Clinical utility of intraoperative Arterial Spin Labeling for resection control in brain tumor surgeries, a 3T study.

Marta Calvo-Imirizaldu1, Verónica Aramendia-Vidaurreta1,2, Marta Vidorreta3, Reyes García-Eulate1,2, Pablo Domingez Echeverri1,2, Josef Pfeuffer4, Bartolome Bejarano5, Lain Hermes Gonzalez-Quarante5, Antonio Martinez-Simon6, and María Fernández-Seara1,2
1Radiology, Clínica Universidad de Navarra, Pamplona, Spain, 2IDISNA, Pamplona, Spain, 3Siemens Healthcare, Madrid, Spain, 4Application Development, Siemens Healthcare, Erlangen, Germany, 5Neurosurgery, Clínica Universidad de Navarra, Pamplona, Spain, 6Anesthesia and Intensive Care, Clínica Universidad de Navarra, Pamplona, Spain


ASL has shown potential to depict residual tumor compared to anatomical imaging in previous intraoperative MRI (iMRI) study performed at 1.5T. However, the technique has not been evaluated at higher field, where field inhomogeneities could compromise the labeling efficiency. We aimed to assess feasibility and utility of iMRI-ASL at 3T. To that end, a PCASL sequence was evaluated in 10 patients. In one patient ASL depicted an additional high CBF focus indicating neovascularization (known to correlate with higher grade component) that wasn’t depicted in the anatomical images, favoring the use of ASL in the iMRI setting to achieve maximal resection.

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