Arterial spin labeling (ASL) benefits from both increased intrinsic SNR and reduced T1 relaxation time at higher field strength. However, the implementation of ASL at 7T is challenging, primarily due to increased SAR, and B1+/B0 inhomogeneity. Recently, United Imaging Healthcare introduced a 5T whole-body scanner. 5T might be a superior field strength for ASL due to the improved SNR compared to 3T, and less severe B1+/B0 inhomogeneity and reduced SAR compared to 7T. This study demonstrated the feasibility of high-resolution ASL at 5T, and the results showed superior SNR compared to 3T.
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