There are two approaches proposed to calculate cerebral blood flow (CBF) and arterial transit time (ATT) accurately, while ensuring sufficient SNR. One is time-encoded (TE) and the other is sequential variable-TR (vTR) pseudo-continuous arterial spin labeling (PCASL). In this study, we measured SNR, CBF, and ATT from these two methods and compared and verified their validity in 5 healthy subjects. The higher SNR was secured in TE-PCASL compared to vTR-PCASL. On the other hand, ATT calculated from vTR-PCASL showed higher correlation coefficient with reference compared with TE-PCASL. The CBF calculated from both schemes showed high correlation coefficient with reference.
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