Image follow-up for intervention effectiveness of osteoarthritis is necessary to avoid or slow down the development of joint space stenosis, bone sclerosis and osteophyte formation. Compared to ZTE-MRI with the feature of nominal zero echo time, MAGIC, synthetic MRI, offers not only anatomical structure images but also T1, T2, and PD maps. We found a significant correlation between joint space value and meniscus volume in reflection of antagonism effect of joint space and surrounding tissues. Proton density weighted synthetic MR images (PD-MAGIC) offered as good as ZTE-MR structure images and might supplement quantitative information clinically to improve follow-up diagnostic performance.
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