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Abstract #4620

In vivo Feasibility of Three-Dimensional Simultaneous Quantitative T1-T2-T2* Mapping (SQUMA) for Knee Cartilage

Renchi Ma1, Huiyu Qiao2, Xinrong Qiao1, Huijun Chen2, Xihai Zhao2, and Zhuozhao Zheng1
1Department of Radiology, Beijing Tsinghua Changgung Hospital, School of Medicine, Tsinghua University, Beijing 102218, China, Beijing, China, 2The Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China, Beijing, China


T1, T2, and T2* mapping provide valuable information for evaluating joint cartilage. However, few studies simultaneously quantified T1, T2, and T2* map to evaluate knee cartilage. In this study, a three-dimensional (3D) simultaneous quantitative T1-T2-T2* mapping (SQUMA) sequence is utilized in knee cartilage. Excellent correlation and good consistency in measuring T1, T2 and T2* values were found between 3D SQUMA sequence and referenced sequences in phantom studies. The T1, T2 and T2* values of knee cartilage were 949.90±82.59 ms, 36.85±2.25 ms and 27.89±5.74 ms, respectively, with good repeatability. 3D SQUMA sequence is feasible for in vivo evaluation of knee cartilage.

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