Abstract #4620

In vivo Feasibility of Three-Dimensional Simultaneous Quantitative T1-T2-T2* Mapping (SQUMA) for Knee Cartilage

Renchi Ma¹, Huiyu Qiao², Xinrong Qiao¹, Huijun Chen², Xihai Zhao², and Zhuozhao Zheng¹

¹Department of Radiology, Beijing Tsinghua Changgung Hospital, School of Medicine, Tsinghua University, Beijing 102218, China, Beijing, China, ²The Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China, Beijing, China

Synopsis

T1, T2, and T2* mapping provide valuable information for evaluating joint cartilage. However, few studies simultaneously quantified T1, T2, and T2* map to evaluate knee cartilage. In this study, a three-dimensional (3D) simultaneous quantitative T1-T2-T2* mapping (SQUMA) sequence is utilized in knee cartilage. Excellent correlation and good consistency in measuring T1, T2 and T2* values were found between 3D SQUMA sequence and referenced sequences in phantom studies. The T1, T2 and T2* values of knee cartilage were 949.90±82.59 ms, 36.85±2.25 ms and 27.89±5.74 ms, respectively, with good repeatability. 3D SQUMA sequence is feasible for in vivo evaluation of knee cartilage.

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