Abstract #4619

T2 map segmentation into the deep, intermediate, and superficial layers when staging of patellar cartilage chondromalacia

Elena Voronkova^1,2, Petr Menshchikov^3,4, Ilya Melnikov¹, Andrei Manzhurtsev^1,4, Maxim Ublinskii¹, Denis Vorobyev¹, Dmitriy Kupriyanov³, and Tolib Akhadov¹

¹Clinical and Research Institute of Emergency Pediatric Surgery and Trauma, Moscow, Russian Federation, ²National Research Nuclear University MEPhI, Moscow, Russian Federation, ³Philips Healthcare, Moscow, Russian Federation, ⁴Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russian Federation

Synopsis

This paper has demonstrated the benefits of segmentation into the deep, intermediate, and superficial layers in analysis of T2 maps of patellar cartilage with chondromalacia. In the deep and intermediate layers, the Т2 values were significantly different in all the patients groups, while the T2 values in the superficial layer did not depend on the disease grade. Compared with the whole cartilage assessment, this approach increased the sensitivity and specificity of chondromalacia staging by 17% and therefore can significantly increase the clinical efficiency of T2 mapping.

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