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Abstract #4625

Evaluate Articular Cartilage in Early-Stage Knee Osteoarthritis with a Two-Compartment Hybrid Multidimensional MR Imaging Method

Peng Luo1, Wentao Hu2, Guanwu Li1, and Yongming Dai2
1Department of Radiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China, 2United Imaging Healthcare, Shanghai, China


Evaluation of early-stage knee osteoarthritis (OA) has long been of wide concern, while MRI has proved its value in this field by the richness of contrasts and non-invasive nature. However, MRI detection for composition change in OA still calls for deeper researches. ADC and T2 measured by conventional MRI are only an average of intra-voxel components and assumed to be independent. However, by performing a hybrid multidimensional MR imaging (HM-MRI) method, an implied correlation between ADC and T2 in articular cartilage has emerged. Moreover, Vnormal might offer extra information in detecting cartilage degeneration at early stage of OA than conventional ADC/T2 parameters.

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