This study demonstrated that intravoxel incoherent motion (IVIM) and dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) can effectively estimate hepatic pathophysiological processes in a rat model with intestinal ischemia reperfusion (IIR) induced hepatic injury. The changes in microcirculation and perfusion were considered the major factors of IIR-induced hepatic injury. IVIM derived parameters of f and D* as well as DCE related parameter of Ve and Ktrans revealed high sensitivity to histological change, implying that IVIM and DCE-MRI might be an effective tool to evaluate the process of IIR-induced hepatic injury.
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