Abstract #4654

Distinction of compensated stage of liver cirrhosis in patients with chronic hepatitis B using IDEAL-IQ Magnetic Resonance Imaging

Hongyi Li¹, Huang lesheng¹, Jun Chen¹, Weiyin Vivian Liu ², Jinghua Jiang¹, Kaili Cai¹, Tianzhu Liu¹, Wanchun Zhang¹, Jiahui Tang¹, Kailian Yang¹, Se Peng³, and Dan Li⁴

¹Radiology, Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China, ²MR Research, GE Healthcare, Beijing, China, ³Clinical Lab, Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China, ⁴Hepatology, Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China

Synopsis

The purpose was to evaluate the feasibility of IDEAL-IQ in distinction of patients with early liver cirrhosis(compensated stage). Sixty CHB patients with compensated cirrhosis conformed by liver biopsy and twenty healthy controls were recruited. FF and R2^* of IDEAL-IQ sequence were analyzed between CHB compensated cirrhosis patients and volunteers. Correlations between FF and R2^* and ALT, INR values were analyzed in CHB patients with compensated cirrhosis. R2^* was statistically different between compensated cirrhosis patients and volunteers (p<0.01) with AUC of 0.726. The correlations between FF and ALT, INR were both fair(0.268, p=0.03 and -0.351, p<0.01).

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