Distinction of compensated stage of liver cirrhosis in patients with chronic hepatitis B using IDEAL-IQ Magnetic Resonance Imaging
Hongyi Li1, Huang lesheng1, Jun Chen1, Weiyin Vivian Liu 2, Jinghua Jiang1, Kaili Cai1, Tianzhu Liu1, Wanchun Zhang1, Jiahui Tang1, Kailian Yang1, Se Peng3, and Dan Li4
1Radiology, Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China, 2MR Research, GE Healthcare, Beijing, China, 3Clinical Lab, Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China, 4Hepatology, Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China
The purpose was to evaluate the feasibility of IDEAL-IQ in distinction of patients with early liver cirrhosis(compensated stage). Sixty CHB patients with compensated cirrhosis conformed by liver biopsy and twenty healthy controls were recruited. FF and R2* of IDEAL-IQ sequence were analyzed between CHB compensated cirrhosis patients and volunteers. Correlations between FF and R2* and ALT, INR values were analyzed in CHB patients with compensated cirrhosis. R2* was statistically different between compensated cirrhosis patients and volunteers (p<0.01) with AUC of 0.726. The correlations between FF and ALT, INR were both fair(0.268, p=0.03 and -0.351, p<0.01).
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