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Abstract #4656

Quantitative T1 and R2* mapping in the evaluation of renal function for diabetic nephropathy patients

Huijian Lu1, Hongmei Gu1, Fangfang Shang1, Li Yuan1, Xinquan Wang1, Weiqiang Dou2, and Weiyin Vivian Liu2
1Affiliated Hospital of Nantong University, Nantong, China, 2MR Research, GE Healthcare, Beijing, China


Renal T1 and R2* mapping were performed on 55 diabetic nephropathy (DN) patients , 20 healthy volunteers(HVs)and 10 diabetes mellitus (DM) patients to explore the clinical potential in assessing renal function. While comparable T1 and R2* values of renal cortex were found between HVs and DM patients, DN patients showed significantly increased T1 and R2* values of renal cortex relative to HVs and DM patients. Both T1 and R2*metrics were also significantly correlated with renal function. Therefore, quantitative T1 and R2* mapping might be considered effective measures in evaluating renal function for DN patients.

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