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Abstract #4657

Can extracellular volume fraction assess liver fibrosis? A preliminary Gd-EOB-DTPA-enhanced MRI study

Pin Yang1, YanLi Jiang1, Jie Zou1, Miao Chang1, Jing Zhang1, and Kai Ai2
1Department of Magnetic Resonance, LanZhou University Second Hospital, Lanzhou, China, 2Philips Healthcare, Xi’an, China


This study evaluates the feasibility of extracellular volume fraction (ECV) in judging liver fibrosis, analyzes the interaction between ECV and liver function.The method is to calculate ECV in different degrees of liver function and compare the correlation between ECV and serum albumin. Our research shows that ECV20min had no significant difference among Child-Pugh A, Child-Pugh B and Child-Pugh C, there was a weak correlation with serum albumin. Therefore, we consider that ECV of hepatobiliary phase will not be affected by liver function when Gd-EOB-DTPA is used to evaluate liver fibrosis, it may be a reliable tool in assessing liver fibrosis.

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