Diffusion metrics from brain Diffusion Tensor Imaging (DTI) characterise axonal structure and include fractional anisotropy (FA), axial diffusivity (AD) and radial diffusivity (RD). Cross-sectional studies of DTI metric maps apply voxel-based statistical analysis of the metric values generated by standard MRTrix and FSL algorithms and assumes that the global values for these metrics are consistent across the populations analysed. This study found that inter-subject global levels vary appreciably for the full range of diffusion metrics. Removal of the variance associated with the global levels markedly improved the statistical inference for differences in a study of ME/CFS patients and healthy controls.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords