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Abstract #4709

Experimental study on intracranial gadolinium deposition in rats after linear conversion to macrocyclic gadolinium contrast agent  

xucong wang1, bing chen2, jian li2, zhen hua wang 1, and Xiaocheng Wei3
1ningxia medical university, yinchuan, China, 2Ningxia Medical University General Hospital, yinchuan, China, 3GE Healthcare, Beijing, China

Synopsis

To investigate the changes of intracranial gadolinium deposition in rats with linear gadolinium deposition after continuous injection of large ring gadolinium contrast agent. The intracranial gadolinium deposition in these rats increased but was relatively small. The DCN T1 value measured on MRI ensemble sequence scan images was significantly negatively correlated with gadolinium concentration in cerebellar DCN. (ALL P values were less than 0.05).

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Keywords