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Abstract #4766

Effect of Meditation on Brain Function During an Attention Task Using ASL and BOLD fMRI

Yakun Zhang1, Shichun Chen1, Zongpai Zhang1, Wenna Duan1, Li Zhao2, George Weinschenk1, Wen-Ming Luh3, Adam Anderson4, and Weiying Dai1
1Department of Computer Science, State University of New York at Binghamton, Binghamton, NY, United States, 2College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China, 3National Institute on Aging, National Institutes of Health, Baltimore, MD, United States, 4Department of Human Development, Cornell University, Ithaca, NY, United States


The effect of meditation on brain functional activation when engaged in an attention task was evaluated longitudinally using dASL and BOLD fMRI in nine healthy subjects. Functional activation before and after meditation practice was compared and the change of functional activation was correlated with practice time. Using dASL, functional activation in the occipital region was significantly reduced; more practice time was associated with more reduced activation in the mediofrontal, temporal, and precuneus regions. Using BOLD fMRI, no significant activation was found. The findings suggest that dASL has superior performance in detecting task performance and that meditation can improve brain efficiency.

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