Meeting Banner
Abstract #4768

Evaluation of traumatic brain injury in pigs using a novel cross-group temporal correlation analysis

Wenwu Sun1, William Reeves1, Madison Fagan2, Christina Welch2, Kelly Scheulin2, Sydney Sneed2, Franklin West2, and Qun Zhao1
1Department of Physics and Astronomy, University of Georgia, Athens, GA, United States, 2Regenerative Bioscience Center and Department of Animal and Dairy Science, University of Georgia, Athens, GA, United States


Traumatic brain injury (TBI) can lead to dynamic changes in functional network activity that can be assessed by functional magnetic resonance imaging (fMRI). In this study, we utilized a novel temporal correlation analysis approach to evaluate a novel microbiome transplantation treatment effect on network connectivity in a translational porcine. Sparse dictionary learning (sDL) and independent component analysis (ICA) were applied to both a full dataset (TBI and sham) and the Sham-only dataset, resulting in four groups of results. Consistency was observed across the four results, indicating that evaluation of treatment effects can be achieved through the proposed temporal correlation analysis.

This abstract and the presentation materials are available to members only; a login is required.

Join Here