Double-echo steady-state (DESS) sequences are a promising candidate for diffusion weighted imaging (DWI) free of geometric distortions. The design of diffusion-weighted DESS (dwDESS) sequences allows waveform variations for the diffusion weighting gradient GD. While dwDESS sequences were originally introduced with unipolar GD, also bipolar or higher order GD are possible. A balanced GD (i.e., with nulling zeroth momentum) typically necessitates a spoiler gradient to suppress banding artefacts, which additionally increases the degrees of freedom in the design of dwDESS sequences. This study explores different dwDESS sequence variants according to predefined optimization criteria.
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