Metabolic alterations specific to glioma can be imaged by MR spectroscopic imaging (MRSI). Adiabatic spin-echo (ASE) MRSI enables spectral editing for specific metabolites with uniform excitation over whole-brain but needs long TR at 7T due to specific absorption rate which results in long acquisition times for high spatial resolution. Acceleration of ASE can be obtained with non-cartesian compressed sense MRSI (ECCENTRIC) acquisition. Here we evaluate the performance of ASE-ECCENTRIC metabolic imaging in glioma patients. We expect that enhanced spectral sensitivity, specificity and high spatial resolution of ASE-ECCENTRIC will improve diagnosis, prognostication, and treatment response monitoring in glioma patients.
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