Abstract #4868

Comparison of 4D, 2D, and 1D phase-contrast MRI quantification of aortic pulse wave velocity in healthy adults

Erin K Englund¹, Takashi Fujiwara¹, Kelly B Jarvis², Michael Markl², Daniel Enge³, Jane E.B. Reusch⁴, and Alex J Barker¹

¹Radiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, ²Radiology, Northwestern University, Chicago, IL, United States, ³Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, ⁴Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Synopsis

Pulse wave velocity (PWV) is an important measure of cardiovascular health, related to vascular stiffness. Aortic PWV can be evaluated with a variety of MRI methods, however a direct comparison of PWV results quantified from 4D flow, 2D phase contrast (PC), and 1D projection PC MRI has not been performed. Here, PWV derived from 4D, 2D, and 1D-PC MRI acquisitions and associated analysis strategies were compared in the aortic arch. Relative agreement was observed among methods. 2D-PC PWV derived from the flow-area approach had substantial variability, likely due to the limited spatial/temporal resolution, and user-dependence of analysis.

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