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Abstract #4873

Follow-up versus baseline 4D flow-derived in vivo hemodynamic parameters stratify descending aorta dissection patients with enlarging aortas

Stanley Chu1, Ozden Kilinc 2, Elizabeth Weiss2, Kelly Jarvis2, Christopher Mehta 2, Chris Malaisrie 2, Andrew Hoel2, Maurice Pradella 2, Bradley Allen2, and Michael Markl2,3,4
1Radiology, Northwestern University, Chicago, IL, United States, 2Northwestern University, Chicago, IL, United States, 3Siemens Healtineers, Erlangen, Germany, 4Cryolife Inc., Kennesaw, GA, United States


Increasing aorta diameter in type B aortic dissection (TBAD) patients is associated with adverse clinical outcomes. Our study evaluates true and false lumen (TL, FL) hemodynamics (kinetic energy (KE), maximum velocity (MV), forward flow (FF), and reverse flow (RF) in baseline and follow-up thoracic aorta 4D flow (4DF) MRI. Baseline aortic diameter does not correlate with aortic growth rate, while FL-total KE, FF, and RF correlate negatively. At follow-up, larger increases in FL-total KE, total FF, KE ratio and FL-mean MV correlate positively with aortic growth rate. Investigating hemodynamic changes in follow-up 4DF may be useful for evaluating TBAD patients.

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