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Abstract #4922

Test-Retest Reproducibility of Cerebrovascular Dual-venc 4D Flow MRI

Jackson E. Moore1, Kristina M. Zvolanek1, Maria Aristova1, Ramez Abdalla1, Ann Ragin1, Eric Russell1, Fan Caprio2, Sameer A. Ansari1, Susanne Schnell1,3, and Michael Markl1
1Radiology, Northwestern University, Chicago, IL, United States, 2Neurology, Northwestern University, Chicago, IL, United States, 3Institute of Physics, University of Greifswald, Greifswald, Germany

Synopsis

Cerebrovascular dual-venc 4D Flow MRI has utility in evaluating intracranial hemodynamics - benefitting from full circle of Willis (CoW) volumetric coverage, time-resolved, three-directional velocity encoding, and velocity dynamic range. Analysis of hemodynamic measures was completed using a comprehensive, semi-automated vessel identification and segmentation workflow for 10 subjects who underwent two scans within 30 days. Test-retest analysis of cerebrovascular dual-venc 4D Flow MRI and measures of CoW 3D flow dynamics demonstrated excellent repeatability for flow and peak velocity measures and lower reproducibility for pulsatility and resistive indices. Future work may include a larger cohort or more advanced analysis of velocity-derived parameters.

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Keywords