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Abstract #5026

MC-ECLIPSE for arbitrary ROI shaping and whole brain shimming for 3D MRSI

Chathura Kumaragamage1, Peter B Brown1, Scott McIntyre1, Terence W Nixon1, Henk M De Feyter1, and Robin A de Graaf1
1Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States

Synopsis

ECLIPSE, a pulsed second order gradient insert can provide robust lipid suppression over an elliptical ROI for applications in human brain MRSI. While ECLIPSE provides excellent axial slice coverage for brain shapes that closely resemble an ellipse, coverage can be compromised for other head shapes. The development of an ECLIPSE gradient coil in combination with a 54-channel multi-coil array (MC-ECLIPSE), that allows B0 field shaping for arbitrary ROI generation is presented. Simulation results demonstrate that near-perfect (99%) axial slice coverage is achievable with MC-ECLIPSE, for a wide range of highly asymmetrical brain and head shapes.

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