Abstract #5027

Spatial encoding with a 48-ch Transcranial Magnetic Stimulation coil array: Application to diffusion imaging

Jason Peter Stockmann^1,2, Lucia Navarro de Lara¹, Mohammed Daneshzand¹, Qinglei Meng¹, Congyu Liao³, Hong-Hsi Lee^1,2, Lawrence L Wald^1,2, Berkin Bilgic^1,2, Susie Huang^1,2, and Aapo Nummenmaa^1,2

¹A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ²Harvard Medical School, Boston, MA, United States, ³Lucas Center, Stanford University, Stanford, CA, United States

Synopsis

We show that multi-channel TMS (mTMS) probe arrays can be used to generate B-fields inside the head for spatial encoding in concurrent TMS/MRI studies. We assess the field-synthesis capability of a 48-ch mTMS array for diffusion imaging and spatial encoding more broadly. Proof-of-concept diffusion imaging experiments on a 3T scanner using a 3-axis TMS probe achieve spatially-varying b-values >500 s/mm² at the depth of the peripheral gray matter using only 4A of current. We consider the potential for scaling up to 200A for studies of gray matter microstructure.

This abstract and the presentation materials are available to members only; a login is required.

Join Here