Meeting Banner
Abstract #0034

Cerebrovascular reactivity in choroid plexus

YUECEN JIN1, Monroe Turner2, Kaisha Hazel3, Yuguang Zhao2, Beini Hu1, Dema Abdelkarim2, Binu Thomas4, Bart Rypma2, Hanzhang Lu3, and Peiying Liu1
1University of Maryland, Baltimore, Baltimore, MD, United States, 2University of Texas at Dallas, Richardson, TX, United States, 3Johns Hopkins University, Baltimore, MD, United States, 4University of Texas Southwestern Medical center, Dallas, TX, United States

Synopsis

Keywords: Neurofluids, Arterial spin labelling, Aging, Blood vessels, Neuro, Neurofluids, Perfusion, Vascular

Motivation: Choroid plexus (CP) plays an important role in the production of CSF and the formation of the blood-CSF barrier, but its vascular function is unclear.

Goal(s): We aim to quantify cerebrovascular reactivity (CVR) of CP in normal controls.

Approach: We applied PCASL with 5%CO2 inhalation in 92 subjects and compared CVR in gray matter, white matter and CP between young and old subjects.

Results: CVR of CP was significantly lower than that of gray and white matter, but showed no age-related difference.

Impact: This work provides a reference for future studies on CVR changes of CP in pathological conditions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords