Keywords: Flow, Cardiovascular, Pulmonary Hypertention
Motivation: There is a lack of noninvasive methods to differentiate between different Pulmonary Hypertension Groups/types. Such differentiation is clinically critical because treatments of one group can be harmful to another.
Goal(s): We investigated a new noninvasive 4D Flow MRI-based method to differentiate between Pulmonary Arterial Hypertension (PAH) and Pulmonary Venous Hypertension (PVH), currently distinguished conclusively only through invasive catheterization.
Approach: Our study focused on analyzing 3D vortex flow and its energetics in the left pulmonary artery (LPA) using 4D Flow MRI.
Results: We found significant differences in vortex characteristics between PVH and PAH patients, with PVH showing larger vortex cores and higher energetics.
Impact: These findings suggest the potential of LPA vortex flow analysis as a noninvasive diagnostic marker for distinguishing between PAH and PVH and possibly assessing disease severity.
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