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Abstract #0099

MRI-based analysis of the blood flow in the left ventricle: 2D geometry-prescribed Cine-MRI based model versus 4D-Flow CMR

Delphine Perie1, Agathe Bedoux1, Pierre Dubois1, and Sebastien Leclaire1
1Mechanical Engineering, Polytechnique Montreal, Montreal, QC, Canada

Synopsis

Keywords: Flow, Cardiovascular, Analysis/Processing, Data Processing, Flow, Heart, In Silico, Modelling, Simulation/Validation, Simulations, Velocity & Flow

Motivation: 4D-Flow CMR allows to analyze 3D blood flow patterns in the left ventricle, however it requires time-consuming acquisitions and complex pre and post-processing.

Goal(s): The objective is to develop a method to analyze blood flow patterns in the left ventricle without these disadvantages.

Approach: Using Cine-MRI and patient-specific modelling techniques, we introduced a new and semi-automated method to simulate the blood flow inside the left ventricle. Accuracy of the developed method was evaluated by comparing the results to 4D-Flow CMR analysis performed on one healthy subject.

Results: Both techniques showed similar blood flow patterns and comparable hemodynamics parameters.

Impact: This patient-specific model is a relatively simple and time-saving method allowing blood flow analysis in the left ventricle based on Cine-MRI acquisition. It may be used to characterize blood flow in patients with heart disease at rest or under stress.

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Keywords