Abstract #0189

Potential of phase-based electrical conductivity in evaluating lumbar intervertebral disc degeneration

Khin Khin Tha¹, Maho Kitagawa², Daiki Sakamoto², Hiroyuki Hamaguchi³, and Ulrich Katscher⁴

¹Global Center for Biomedical Science and Engineering, Hokkaido University Faculty of Medicine, Sapporo, Japan, ²Laboratory for Biomarker Imaging Science, Hokkaido University Graduate School of Biomedical Science and Engineering, Sapporo, Japan, ³Hokkaido University Graduate School of Biomedical Science and Engineering, Sapporo, Japan, ⁴Philips Research Laboratories, Hamburg, Germany

Synopsis

Keywords: Electromagnetic Tissue Properties, Electromagnetic Tissue Properties, intervertebral disc, lumbar, degeneration

Motivation: Visual assessment of T2-weighted image constitutes the mainstay in evaluating the severity of intervertebral disc degeneration (IVD) degeneration. Quantitative MRI indices that strongly correlate with the degree of degeneration are lacking.

Goal(s): This study aimed to evaluate if electrical conductivity (σ) derived from phase-based EPT was sensitive to the degenerative changes of lumbar IVD.

Approach: EPT was conducted, along with DWI, T1ρ, and T2* imaging, in 54 patients with lumbar IVD degeneration. The diagnostic performance of σ was compared with that of ADC, T1rho, and T2*.

Results: σ can compliment the other quantitative MRI indices in evaluating lumbar IVD degeneration.

Impact: This is the first study which evaluated the potential clinical usefulness of σ derived from phase-based EPT in evaluating the severity of degeneration of lumbar IVD.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.