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Abstract #0199

Water/fat separated Prostate Diffusion-Weighted Imaging using Dixon-encoded multi-shot EPI with structured low-rank reconstruction

Yiming Dong1, David Atkinson2, Kirsten Koolstra3, Matthias J.P. van Osch1, and Peter Börnert1,4
1C.J. Gorter MRI Center, Department of Radiology, LUMC, Leiden, Netherlands, 2Centre for Medical Imaging, University College London, London, United Kingdom, 3Philips, Best, Netherlands, 4Philips Research Hamburg, Hamburg, Germany

Synopsis

Keywords: Prostate, Prostate

Motivation: Conventional single-shot EPI (ssh-EPI) is fast, but often causes geometric distortions, especially near the rectum.

Goal(s): In this research, a Dixon-msh-EPI technique is validated for prostate Diffusion-weighted Imaging (DWI).

Approach: Dixon-msh-EPI is proposed to reduce such distortions, while jointly separating water/fat components by a special structured low-rank reconstruction that also corrects shot-to-shot phase variations.

Results: Experiments were conducted on 7 healthy male volunteers using a 3T scanner comparing DW-ssh-EPI and Dixon-msh-EPI performance. The Dixon-msh showed significantly reduced geometric distortion and effective fat signal suppression, as scored by two readers. While both methods provided comparable image quality, Dixon-msh-EPI demonstrated improved motion-correction and geometric accuracy.

Impact: Dixon-msh-EPI offers improved prostate DWI by significantly reducing geometric distortions and enhancing across b-value registration. This technique could lead to more accurate diagnoses and has the potential to refine clinical MRI protocols, emphasizing precision in prostate diffusion imaging.

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