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Abstract #0205

Amide-proton transfer weighted imaging combined with time-dependent diffusion weighted imaging for evaluation of breast tumors

Xiaoyan Wang1, Yan Zhang1, Jingliang Cheng1, Liangjie Lin2, Zhigang Wu2, Peng Sun2, Ying Hu1, Anfei Wang1, Ruhua Wang1, Yong Zhang1, Ying Li1, Kun Zhang1, and Wenhua Zhang1
1The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2Philips Healthcare, Beijing, China

Synopsis

Keywords: Breast, Breast

Motivation: Breast cancer is a complex and heterogeneous disease, and its different subtypes show very different biological characteristics, which will also affect the choice of treatment.

Goal(s): The objective of this study was to explore the value of APTWI combined with td-MRI in evalution of breast tumors.

Approach: The performance of APTWI was compared to conventional td-MRI in differentiation between benign and malignant breast tumors.

Results: APTWI overperform td-MRI in differentiation between benign and malignant breast tumors. And ADC values derived from td-MRI at different gradient oscillation frequencies show potential diagnostic values in predicting different risk factors in breast cancer.

Impact: These may provide new ideals for the diagnosis, treatment and prognosis evaluation of breast cancer.

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Keywords