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Abstract #0210

Evaluation of Amide Proton Transfer-Weighted Imaging and T2 mapping for preoperative risk stratification of endometrioid adenocarcinoma

Fang Wang1, Lianhua Cheng1, Lingyu Chang1, Dmytro Pylypenko2, Weiqiang Dou2, Dexin Yu1, and Qing Wang1
1Qilu Hospital of Shandong University, Jinan city, Shandong province, China, 2GE Healthcare, Beijing, China, Beijing, China

Synopsis

Keywords: Uterus, Cancer, Amide proton transfer-weighted imaging; T2 mapping ; endometrioid adenocarcinoma; risk stratification

Motivation: Preoperative risk stratification of endometrioid adenocarcinoma (EA) impacts the choice of operative modality and prognosis of patients.

Goal(s): We aimed to perform an accurate and non-invasive preoperative risk stratification method for EA by MRI sequences.

Approach: APTw imaging as well as T2 mapping were included in this study.

Results: The APTw and T2 values showed significant differences between the low- and non-low-risk groups. Combining APTw with T2 mapping achieved the highest diagnostic efficacy in the preoperative risk stratification.

Impact: This suggested that the integrated use of APTw and T2 mapping can be an effective method for the preoperative risk assessment of EA.

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Keywords