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Abstract #0283

Accelerated free-breathing 3D simultaneous Bright and black-blood Whole-Heart Imaging at 0.55T: Comparison to 1.5T.

Anastasia Fotaki1,2, Carlos Castillo-Passi1,3,4, Michael G. Crabb1, Karl K Kunze1,5, Kuberan Pushparajah1, and Rene Botnar1,3,6,7,8
1School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK, London, United Kingdom, 2Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom, 3Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile, 4School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile, 5MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, Camberley, United Kingdom, 6Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile, 7Millennium Institute for Intelligent Healthcare Engineering, Chile, Santiago, Chile, 8Technical University of Munich, Germany; Institute of Advanced Study, Munich, Germany, Santiago, Chile

Synopsis

Keywords: Vessel Wall, Low-Field MRI, bright- and black-blood whole heart, vessel lumen,vessel wall

Motivation: Bright-blood and black-blood MRI is fundamental for the comprehensive assessment of cardiac disease.Low field MRI promises high quality imaging at lower cost and improved patient accessibility.3D bright-blood and black-blood whole-heart imaging applications at low-field are limited.

Goal(s): To implement and evaluate the diagnostic quality of a novel framework for simultaneous 3D whole-heart bright-and black-blood(BOOST) imaging at 0.55T.

Approach: 3D whole-heart BOOST including image-based navigation, motion corrected reconstruction and patch-based denoising was evaluated at 0.55T.Diagnostic capabilities of 3D BOOST was evaluated versus its counterpart at 1.5T.

Results: 3D whole-heart BOOST at 0.55T offers good quality imaging, that is comparable to its counterpart at 1.5T.

Impact: This study demonstrates that high-quality bright- and black-blood 3D whole-heart imaging can be achieved at 0.55T CMR, showing comparable image and diagnostic quality to the current clinical standard in ­both healthy subjects and clinical patients.

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Keywords