Keywords: fMRI Analysis, fMRI (task based), speech, swallowing, fMRI analysis, dynamic imaging
Motivation: SimulScan enables the joint imaging of dynamic oropharyngeal movements during speech and swallowing along with their central control from functional MRI.
Goal(s): The large, complex dataset requires memory-efficient analysis to find the uncover the underlying relationships between the dynamic and functional imaging data.
Approach: Here we develop a memory-efficient implementation of partial least square (PLS) and apply it to a blocked tongue tapping task.
Results: The PLS method separates out correlated motions and brain function for different components of the task.
Impact: SimulScan with PLS analysis can enable the visualization of central control of complex processes such as speech and swallowing. This approach will enable the in-depth study of healthy and disordered speech and swallowing mechanisms in age and disease.
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