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Abstract #0340

Joint learning of optimal acquisition and high quality ADC mapping for low field diffusion-weighted PROPELLER MRI

Jiechao Wang1, Lu Wang1, Chunguang Zhang2, Liangjie Lin3, Congbo Cai1, and Shuhui Cai1
1Xiamen University, Xiamen, China, 2Foshan Ruijiatu Medical Technology Co., Ltd., Foshan, China, 3MSC Clinical & Technical Solutions, Philips Healthcare, Beijing, China

Synopsis

Keywords: Acquisition Methods, Low-Field MRI

Motivation: Adequate image signal-to-noise ratio (SNR) and resolution within a reasonable scan time is challenging for low-field diffusion quantitative MRI.

Goal(s): To present a PROPELLER-acquisition and ADC mapping joint learning neural network to accelerate DWI with improved image SNR and resolution.

Approach: Considering the similar anatomical structure between diffusion-weighted MR images, this work achieved DWI PROPELLER-acquisition optimization and reconstructed high quality ADC maps from data acquired by optimized acquisition using U-net.

Results: In vivo and simulation results demonstrate that our proposed method can generate high SNR and resolution ADC maps within 2 minutes scan time under 0.23T human scanner.

Impact: Joint learning acquisition and quantitative reconstruction based on PROPELLER sampling trajectory using neural network has successfully achieved fast ADC mapping, offering great possibility for quantitative analysis in low-field diffusion MRI.

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