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Abstract #0357

Deep learning radiomic nomogram can distinguish intracranial solitary fibrous tumor from angiomatous meningioma: a multicenter study

Xiaohong Liang1, Xaioai Ke2, Junlin Zhou2, and Liqin Zhao1
1Beijing Tiantan Hospital, Capital Medical University, Beijing, China, 2Lanzhou University Second Hospital, Lanzhou, China

Synopsis

Keywords: Tumors (Pre-Treatment), Machine Learning/Artificial Intelligence

Motivation: A novel and noninvasive method for distinguishing intracranial solitary fibrous tumor (ISFT) from angiomatous meningioma (AM) and predicting patient outcomes is urgent.

Goal(s): To evaluate the value of a MRI-based deep learning radiomic nomogram (DLRN) in distinguishing ISFT from AM and predicting patient outcomes.

Approach: A MRI-based DLRN was developed on training cohort (TC). We then validated it's performance on external validation cohort (EVC). Moreover, we investigated the value of the DLRN in survival analysis.

Results: The performance of DLRN was excellent (0.86 [0.84–0.88]) on EVC. Besides, DLRN was significantly associated with the overall survival (OS) of patients (n=273).

Impact: The proposed DLRN can potentially provide a noninvasive method for neurosurgeon to offer decision support for developing personalized treatment plans and predicting patient outcomes.

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