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Abstract #0380

qDiMo: Domain-conditioned Diffusion Modeling for Accelerated qMRI Reconstruction

Wanyu Bian1,2, Albert Jang1,2, and Fang Liu1,2
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: AI Diffusion Models, Machine Learning/Artificial Intelligence, Rapid MRI, Quantitative MRI, knee, brain

Motivation: Quantitative MRI (qMRI) is time-consuming and requires substantial efforts for acceleration to cut down the acquisition time.

Goal(s): This paper proposes a novel generative AI approach for image reconstruction based on diffusion modeling conditioned on the native data domain.

Approach: Our method is applied to multi-coil quantitative MRI reconstruction, leveraging the domain-conditioned diffusion model within the tissue parameter domain.

Results: The proposed method demonstrates a significant promise for reconstructing quantitative maps at high acceleration factors. Notably, it maintains excellent reconstruction accuracy and efficiency for MR parameter maps across diverse anatomical structures.

Impact: This work demonstrates the feasibility of a new generative AI method for rapid qMRI. Beyond its immediate applications, this method provides potential generalization capability, making it adaptable to inverse problems across various domains.

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Keywords