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Abstract #0448

T1 Contrast-Augmented Single-Spoke Real-Time 4D MRI

Li Feng1,2, Jingjia Chen1,2, Ding Xia3, Hersh Chandarana1,2, and Daniel K Sodickson1,2
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA, New York University Grossman School of Medicine, New York, NY, United States, 3BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, NY, United States

Synopsis

Keywords: MR-Guided Radiotherapy, Radiotherapy, 4DMRI, Real-Time Imaging

Motivation: 4D MRI is a powerful technique for free-breathing volumetric imaging, holding great potential for application in MRI-guided radiotherapy. Traditional 4D MRI typically requires explicit motion detection and data binning for respiratory-resolved reconstruction and commonly employs fast steady-state MRI acquisition, which may not yield optimal contrast.

Goal(s): This work proposes a novel T contrast-augmented, free-breathing, real-time 4D MRI technique.

Approach: The proposed technique improves image contrast through highly-accelerated inversion recovery-prepared acquisition and reconstruction of real-time 4D images at a sub-second temporal resolution without requiring explicit motion compensation.

Results: T1 contrast-augmented real-time 4D MRI demonstrated improved image contrast over conventional 4D MRI with steady-state acquisition.

Impact: The contrast-augmented real-time 4D MRI technique proposed in this work can improve image contrast for free-breathing imaging without requiring explicit motion detection, data binning and respiratory motion compensation. It holds great potential for various applications, such as MRI-guided radiotherapy.

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Keywords