Keywords: Cartilage, Osteoarthritis, Relaxometry
Motivation: Weight loss has been shown to be beneficial for knee symptoms and reducing cartilage degeneration.
Goal(s): To examine the impact of weight-loss in obese subjects on articular cartilage in the tibiofemoral joint using T2 relaxation time mapping.
Approach: Knees of 65 obese patients undergoing either bariatric surgery or conservative weight loss regimens were imaged at 3T before and three years after treatment. Changes in T2 were assessed in tibiofemoral cartilage.
Results: A reduction in body mass index (BMI) was associated with shortened T2 values in tibia, indicating that weight loss may result in improved cartilage quality.
Impact: The findings provide supporting evidence for the benefits of weight loss for cartilage health and have relevance in the context of osteoarthritis prevention and treatment.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords