Abstract #0540

Towards Reproducible Intravoxel Incoherent Motion (IVIM) Analysis: The ISMRM Open Science Initiative for Perfusion Imaging

Oscar Jalnefjord^1,2, Ivan A. Rashid^3,4, Daan Kuppens^5,6, Merel van der Thiel^7,8, Petra van Houdt⁹, Paulien HM Voorter^7,8, Eric T Peterson¹⁰, and Oliver Gurney-Champion^5,6

¹Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ²Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden, ³Medical Radiation Physics, Department of Translational Medicine, Lund University, Malmö, Sweden, ⁴Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden, ⁵Department of Radiology and Nuclear Imaging, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands, ⁶Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, Netherlands, ⁷Department of Radiology & Nuclear Medicine, School for Mental Health & Neuroscience, Maastricht University Medical Center, Maastricht, Netherlands, ⁸School for Mental Health & Neuroscience, Maastricht University, Maastricht, Netherlands, ⁹Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands, ¹⁰Biosciences, Neuroscience Program, SRI International, Menlo Park, CA, United States

Synopsis

Keywords: Software Tools, Perfusion, Reproducible research

Motivation: Lack of validated and open-source intravoxel incoherent motion (IVIM) post-processing and fitting code is hindering reproducible research, limiting the validation and large-scale roll-out of IVIM imaging.

Goal(s): To create an open-source code repository for IVIM-related code.

Approach: Scientists interested in IVIM are encouraged to upload their code to our open-source code repository built by the ISMRM OSIPI task force 2.4, where automated testing and evaluation based on reference data are used to enable quality control of the code.

Results: As of November 2023, 19 code contributions have been submitted by 6 different institutes, all passing automated testing.

Impact: The work of ISMRM OSIPI task force 2.4 enables an open-source platform for validated code relevant to intravoxel incoherent motion (IVIM) imaging, thus reducing duplicate development, improving reproducibility, and serving as a benchmark for future methods.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.